|Cancer Society of America | Testicular Cancer | Cause | Treatment | Symptoms | Diagnosis | Prevention, Early Detection
Testicular cancers are uncommon malignancy in general population.
However, primary testicular tumors are the most common solid malignant
tumors in men between ages 20 and 35 years old. In the United States,
incidence of testicular cancers is about 9,000 cases with about 300 to 400
deaths annually. The lifetime risk of Americans to develop testicular cancer
is about 1 in every 265 and the risk of dying is just 1 in 5,000.
Testicular cancers are mostly 95% germ cell tumors that are divided into two
major types; pure seminoma and nonseminomatous germ cell tumors. These
tumors are further subdivided into several subtypes depending on the histological
features. The course and prognosis of the disease depend on to which subtype
Testicular cancer has been studied for a long time, but the exact cause of the disease is still unknown. Scientists consider multiple
factors that predisposes a patient to develop this germ cell-derived tumor. One factor is genetic predisposition. Several studies
revealed that 1st degree relatives have higher risk of developing this cancer compared to the general population. A son of an affected
patient has 5 times increased risk while a sibling of an affected patient has up to 8 times increased risk of developing the disease.
A condition called cryptorchidism also carries high risk of developing this cancer. It is a condition wherein the testis fails to descend
from the abdomen to the scrotum during the fetal period. This is also linked to exposure of diethylstilbestrol which is a chemical
pointed out to be the cause of such condition.
There are other risk factors correlated with higher risk to develop this disease, but none are more important than a prior history of
testicular cancer. Patients who were already diagnosed to have testicular cancer have a 500-fold higher rate to develop second primary
testicular tumor compared to the general population.
|Cancer Society Of America is a qualified 501(c)(3) non profit tax-exempt charity organization located in Maryland. All your contributions, donations and charities are fully
tax-deductible. Please consult your tax advisor for all your donations.
Copyright © 2016 Cancer Society of America, Inc.
|Let's Together Fight Cancer
AND Make A Difference!